Angiotensin converting enzyme inhibitors (ACEIs) are those drugs which are frequently used for the treatment of cardiovascular disorders including hypertension and heart failure. This group of drugs diminishes blood pressure and oxygen demand by dilating blood vessels. These drugs principally inhibit an angiotensin converting enzyme which is an integral part of RAAS (Renin-angiotensin-aldosterone system). The detailed mode of action is described in the following diagram.
Classification of ACEIs:
Here is a classification of ACEIs with description.
|Type of Group||Drug Name||Dosage Form||Strength||Uses||Side Effects|
|Tablets||12.5, 25, 50, and 100 mg||Myocardial Infaction , Hypertneion, CHF and Albuminuria||Dry Cough, Nephrotoxicity, Angeoedema, Hypotension and Hyperkalimia|
|Tablets||10, 20 and 40mg|
|Tablets||5, 10, 20, and 40 mg.|
|Tablets , Injection||2.5, 5, 10, and 20 mg. 1.25 mg/ml|
|Tablet||2.5, 5, 10, 20, 30 and 40 mg|
|Tablets||5, 10, 20 and 40 mg|
|Capsules Or Tablets||1.25, 2.5, 5 and 10 mg|
- Laurence L. Brunton, ed. (2006). “Chapter 30. Renin and Angiotensin – Edwin K. Jackson”. Goodman & Gilman’s The Pharmacological Basis of Therapeutics (11 ed.). McGraw-Hill
- Katzung, B. Basic and Clinical Pharmacology. 11th ed. McGraw Hill Medical, 2009
- Lippincott’s illustrated reviews Pharmacology 5th Edition (Richard A. Harvey)
Copyright 2012 Medimoon.com. All rights reserved. No part of this site can be reproduced without our written permission.