Ebola virus disease is a current outbreak in African countries that has also targeted other countries including United State and England. It has been estimated by Center for Disease Control and Prevention (CDC) that approximately 13,676 cases has been reported as yet from Liberaia, Guinea and Sierra Leone only.
Unfortunately there is no standard treatment that could help in eradication of this infection as a result the rate of mortality and morbidity in continuously escalating.
Here is a list of some drugs that could possibly be used after approval from U.S. Food and Drug Administration in near future. Currently all these drugs are either in pre-clinical studies or in clinical trials.
|No||Name of drug||Phase of Clinical Trials||Manufacturer||Comments|
|01||MVA-BN filo/AdVac||Phase 1 (Starting in 2015)||Johnson and Johnson||Vaccine|
|02||BCX4430||Pre-clinical studies||BioCryst Pharma||RNA-dependent RNA polymerase inhibitor|
|03||Brincidofovir||Phase 2/3 (exploratory)||Chimerix||nucleotide analog|
|Pre-clinical||Inovio Pharma||Polyvalent DNA Vaccine|
|07||rVSV-ZEBOV||Phase 1||New Link Genetics||Vaccine|
|08||Vasicul Vax||Pre-clinical||Profectus Bioscience||Vaccine|
|09||AVI-7537||Phase 1||Sarpeta Therapeutics||Prevent replication of virus|
|10||TLM Ebola||Phase 1||Tekmira|
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