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Early Diabetes Treatment May Prevent Risk Of Heart Diseases

Diabetic patients can prevent themselves from heart diseases by using two treatments that are used to reduce their blood sugar, according to the latest study published in the journal of Clinical Endocrinology and Metabolism (JCEM).

The objective of this study was to determine the effect of lifestyle modification and administration of Metformin (a drug used in"metformin-pills" diabetic patient to lower their blood sugar levels) on triglycerides and cholesterol levels. They concluded that both of these treatments have shown a positive impact on triglycerides and cholesterol levels and can reduce the risk of plaque formation in the blood vessels.

“Cardiovascular disease is the most significant cause of death and disability in people with diabetes,” said the study’s lead author, Ronald Goldberg, MD, of the University of Miami’s Miller School of Medicine. “Our findings demonstrate that the same therapies used to slow the onset of diabetes also may help allay the risk of heart disease.”

During this study researchers investigated 1,645 blood samples of patients suffering from diabetes. All the participants were converted into three groups randomly. The first group received Metformin, the second group received placebo and the third group underwent lifestyle modification.

The researchers evaluated the blood sample at the start of this study and then after one year in order to determine the impact of treatments on the patient’s lipid profile.

The results of this study have been demonstrated in the following table;

Group Received/Admistered Effect
1st Metformin Reduction in low density lipoproteins (LDL)

Levels of high density lipoprotein (HDL) increases

2nd Placebo No significant effect
3rd Lifestyle modification Reduction in low density lipoproteins (LDL)

Levels of high density lipoprotein (HDL) increases

“Preventing or slowing the development of diabetes with these treatments also improves the cholesterol and triglyceride profile of a person’s blood,” Goldberg said. “Thanks to the added benefits of existing diabetes interventions, we stand a better chance of lowering the risk of heart disease in this patient population.”

Source: The Endocrine Society 

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