Using acetaminophen in infancy for pain and fever could increase the risk of asthma in their preschool years according to the latest research published in the journal of Allergy and Clinical Immunology. Researchers conducted this study on 411 Danish children to determine as association between risk of asthma in kids and use of acetaminophen.
“We think it is too early to conclude a causal relationship,” according to senior researcher Dr. Hans Bisgaard, a professor of pediatrics at the University of Copenhagen in Denmark.
Researchers followed 336 children from their date of birth to age seven. They were already more likely to suffer airway problems as their mothers had asthma. Almost 19% children got asthma symptoms at the age of three.
“Bisgaard’s team found that the risk generally went up the more often a child was given acetaminophen in the first year of life. For each doubling in the number of days a baby received the drug, there was a 28 percent increase in the risk of asthma symptoms.”
The risk of asthma was reduced up to 14% in kids at the age of seven and the risk was not increased by using acetaminophen at lesser age.
But this study’s not the last word, Milgrom said. “I don’t think this answers the question. It raises more questions.”
The severity of other respiratory tract infections were more in kids with asthma as suggested by researchers,
The effects of acetaminophen could be temporary as there was no link between asthma and acetaminophen use at the age of 7.
In past various researchers have concluded that children with acetaminophen use are at increased risk of developing asthma but few has also contradict this.
Children taking ibuprofen and naproxen are at risk of asthma according to the recent research.
“We would like to stress,” Bisgaard said, “that the use of this drug indeed is beneficial in the appropriate circumstances.”
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Eskil Kreiner-Møller, MD, Astrid Sevelsted, MSc, Nadja Hawwa Vissing, MD, Ann-Marie Malby Schoos, MD, Hans Bisgaard, MD, DMS, “Infant acetaminophen use associates with early asthmatic symptoms independently of respiratory tract infections: The Copenhagen Prospective Study on Asthma in Childhood 2000 (COPSAC2000) cohort” 2012, doi:10.1016/j.jaci.2012.09.017
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