Therapeutically there is no difference between ferrous sulfate and ferrous gluconate as both forms of irons are prescribed for the treatment of anemia. There is slight difference between these two as ferrous sulfate is inorganic supplement and ferrous gluconate is organic supplement.
The rate of absorption of organic supplements is more in comparison with inorganic supplements so large amount of ferrous sulfate is required to get desired effects. Some patients can better tolerate ferrous gluconate than ferrous sulfate.
So it is better to use ferrous gluconate instead of ferrous sulfate for the treatment of anemia.
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