Researchers have claimed that they have discovered a drug that could be effective against different types of cancers. This drug utilizes different types of pathways to control the abnormal proliferation and multiplication of cells. It’s working shows as different types of drugs working altogether. This drug is an enzyme inhibitor and belongs to tyrosine class.
It would be beneficial to stop signaling of cells at more than one points which could leads to better treatment of cancer. In this way drug resistance can also be avoided. Lab experiments have indicated that this new drugs whose code name is AT13148 can kill different types of cancer including breast, sarcoma and prostate. The findings of this novel research have been published in the journal of Clinical Cancer Research.
Dr Michelle Garrett, from Cancer Research UK’s Cancer Therapeutics Unit at the Institute of Cancer Research in London, said: “Our study shows that this drug is effective against a range of tumour types, and operates by blocking multiple targets.
“These promising results have led to the decision to take the drug into patient trials.”
The discovery of new molecule is due to collaborative effort made by scientists from Astex Pharmaceuticals, the Cancer Research UK company Cancer Research Technology, and the Institute of Cancer Research.
Dr Julie Sharp, Cancer Research UK’s senior science information manager, said: “This is exciting research showing that this experimental drug does the job of several drugs all at once, by targeting numerous weak spots in cancer cells.
“Using one master switch to turn off the different faulty messages forcing cancer cells to keep growing could be an effective way to destroy tumours. It could also reduce the chance of patients becoming resistant to treatment.”
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